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Distillations | Science History Institute

Science History Institute

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Distillations | Science History Institute

Distillations | Science History Institute

Science History Institute

56
Followers
73
Plays
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Each episode of Distillations podcast takes a deep-dive into a moment of science-related history in order to shed light on the present.

Latest Episodes

Preview: We're moving to seasons!

Stay tuned for our upcoming season, dropping in summer 2020!

1 MINFEB. 12
Comments
Preview: We're moving to seasons!

How Philadelphia's Water Pollution Problems Shaped the City

Philadelphia just had the wettest decade on record, and all that precipitation has wreaked havoc on the city’s waterways. Like most old cities, Philadelphia has a combined sewer system—that is, one pipe is used to carry both sewage and stormwater. When it rains a lot, the system gets overwhelmed, forcing the water department to send raw sewage into rivers and creeks. City officials and engineersknew this was going to be a problem when they built the sewer system in the 1800s. The reason why they used a combined system anywaycan be best explained by two forces: knowledge ceilings and path dependency.In this episode we’re going to explore how the city got to this pointand how, in an interesting twist, it led to Philadelphia having one of the most innovative water systems in the country. Philadelphia is home of theDistillationspodcast. For this episode we are going to break down three centuries of water-pollution history in our backyard. It is a special collaboration with thePhiladelphia Inquireras part of their seriesFrom the Source: Stories of the Delaware River. Credits Host:Elisabeth Berry Drago Reporter:Rigoberto Hernandez,Sebastian Echeverri Senior Producer:Mariel Carr Producer:Rigoberto Hernandez Audio Engineer:James Morrison Additional production: Dan Drago Special thanks to the Science History Institutes, oral history department, and the museum team for doing someof the research that went into this episode. This includesRebecca Ortenberg,Christy Schneider,Samantha Blatt,Zackary Biro, and Grey Pierce. Resource List Grabar, Henry. “Tunnel Vision.”Slate, January 2, 2019. Handy, Jam. “Waters of the Commonwealth.” Pennsylvania Sanitary Water Board, 1951. Henninger, Danya. “The Incredible Fairmount Water Works: Explosions, Mark Twain and the Long-Lost Philadelphia Aquarium.”Billy Penn, October 10, 2015. Kummer, Frank. “The Secret Scourge of Climate Change? More Raw Sewage in Philadelphia’s Waterways.”Philadelphia Inquirer, September 13, 2019. Levine, Adam. “Fairmount Water Works.” Philadelphia Water Department Water and Drainage History Course, 2015. Nemiroff, Sydney P., dir. “Road Ahead: Milestone 3.” Philadelphia Department of Records, ca. 1960. Schulman, Alexis. “Sustainable Cities and Institutional Change: The Transformation of Urban Stormwater Management.” PhD diss., Massachusetts Institute of Technology, 2018. Stutz, Bruce. “Philadelphia Is Tackling Its Stormwater Problem.”Yale Environment360 (March 29, 2018).

47 MINENE. 8
Comments
How Philadelphia's Water Pollution Problems Shaped the City

Jane Hodgson

She broke abortion law to try to change it.

12 MIN2019 DIC. 18
Comments
Jane Hodgson

Roe v. Wade v. Rubella

The virus that made America talk about abortion.

51 MIN2019 DIC. 18
Comments
Roe v. Wade v. Rubella

Preview: Roe v. Wade v. Rubella

The virus that made America talk about abortion.

2 MIN2019 DIC. 4
Comments
Preview: Roe v. Wade v. Rubella

Promo: LIVE Halloween show!

Come see Distillations LIVE for our Halloween Spooktacular! The show is Wednesday, October 30th at 7pm at the Science History Institute in Old City Philadelphia.

59 s2019 OCT. 24
Comments
Promo: LIVE Halloween show!

The Alzheimer's Copernicus Problem, Part 1

Almost six million people in the United States have been diagnosed with Alzheimer’s disease. And with baby boomers getting older, those numbers are only expected to rise. This disease, despite being studied by scientists for more than 100 years, has no cure. In our two-part series we first dive into the personal lives of the people at the heart of this disease: the patients and their caregivers. Then we uncover why effective treatments for Alzheimer’s lag so far behind those for cancer, heart disease, and HIV. It turns out that for all the decades researchers have been at war with the disease, they’ve also been at war with each other. Credits Hosts:Alexis Pedrick Reporter:Rigoberto Hernandez Producer:Rigoberto Hernandez Senior Producer:Mariel CarrAudio Engineer:James Morrison Music courtesy of theAudio Network. These songs were used courtesy ofBlue Dot Sessions: "Kalsted,""Stretch of Lonely," "Thin Passage," "Waltz and Fury," "Dash and Slope," "Gilroy Solo," 'House of Grendel," "Uncertain Ground," and "Watercool-Quiet." Research Notes “2019 Alzheimer’s Disease Facts and Figures.” Alzheimer’s Association, 2019. Begley, Sharon. “As Alzheimer’s Drug Developers Give Up on Today’s Patients, Where Is the Outrage?” Stat News. August 15, 2018. Begley, Sharon. “The Maddening Saga of How an Alzheimer’s ‘Cabal’ Thwarted Progress toward a Cure for Decades.” Stat News. June 25, 2019. “Biogen Alzheimer’s Drug Shows Positive Results.” CNBC. July 25, 2018. “The Clinical Trial Journey.” Mayo Clinic. Youtube video. June 5, 2019. Garde, Damian. “Alzheimer’s Study Sparks a New Round of Debate over the Amyloid Hypothesis.” Stat News. July 30, 2018. Hogan, Alex. “The Disappointing History of Alzheimer’s Research.” Stat News. May 21, 2019. Itzhaki, Ruth. “Alzheimer’s Disease: Mounting Evidence That Herpes Virus Is aCause.” The Conversation. October 19, 2018. Keshavan, Meghana. “On Alzheimer’s, Scientists Head Back to the Drawing Board—and Once-Shunned Ideas Get an Audience.” Stat News. July 22, 2019. Li, Yun. “Biogen Posts It’sthe Worst Day in 14 Years after Ending Trial for Blockbuster Alzheimer’s Drug.” CNBC. March 21, 2019. “Lilly Alzheimer’s Drug Does Not Slow Memory Loss: Study.” CNBC. November 23, 2016. “The MacNeil/Lehrer Report; Living with Alzheimer’s.” 1983-04-12, National Records and Archives Administration, American Archive of Public Broadcasting (WGBH and the Library of Congress), Boston and Washington, DC, accessed October 16, 2019. “The MacNeil/Lehrer NewsHour,” 1991-08-16, NewsHour Productions, American Archive of Public Broadcasting (WGBH and the Library of Congress), Boston, MA and Washington, DC, accessed October 22, 2019. Makin, Simon. “The Amyloid Hypothesis on Trial.”Nature. July 25, 2018. Prusiner, Stanley.Madness and Memory: The Discovery of Prions—A New Biological Principle of Disease.New Haven: Yale University Press, 2014. Robakis, Nikolaos, et al. “Alzheimer’s Disease: A Re-examination of the Amyloid Hypothesis.” ALZforum.org. March 26, 1998. Shenk, David. “The Forgetting—Alzheimer’s: Portrait of an Epidemic.” New York: Anchor, 2013. “Virginia Lee and John Trojanowski on the Protein Road Map to Alzheimer’s.” Science Watch. December 2011.

46 MIN2019 OCT. 23
Comments
The Alzheimer's Copernicus Problem, Part 1

The Alzheimer’s Copernicus Problem, Part 2

Almost six million people in the United States have been diagnosed with Alzheimer’s disease. And with baby boomers getting older, those numbers are only expected to rise. This disease, despite being studied by scientists for more than 100 years, has no cure. In our two-part series we first dive into the personal lives of the people at the heart of this disease: the patients and their caregivers. Then we uncover why effective treatments for Alzheimer’s lag so far behind those for cancer, heart disease, and HIV. It turns out that for all the decades researchers have been at war with the disease, they’ve also been at war with each other. Credits Hosts:Alexis Pedrick Reporter:Rigoberto Hernandez Producer:Rigoberto Hernandez Senior Producer:Mariel CarrAudio Engineer:James Morrison Music courtesy of theAudio Network. These songs were used courtesy ofBlue Dot Sessions: "Kalsted,""Stretch of Lonely," "Thin Passage," "Waltz and Fury," "Dash and Slope," "Gilroy Solo," 'House of Grendel," "Uncertain Ground," and "Watercool-Quiet." Research Notes “2019 Alzheimer’s Disease Facts and Figures.” Alzheimer’s Association, 2019. Begley, Sharon. “As Alzheimer’s Drug Developers Give Up on Today’s Patients, Where Is the Outrage?” Stat News. August 15, 2018. Begley, Sharon. “The Maddening Saga of How an Alzheimer’s ‘Cabal’ Thwarted Progress toward a Cure for Decades.” Stat News. June 25, 2019. “Biogen Alzheimer’s Drug Shows Positive Results.” CNBC. July 25, 2018. “The Clinical Trial Journey.” Mayo Clinic. Youtube video. June 5, 2019. Garde, Damian. “Alzheimer’s Study Sparks a New Round of Debate over the Amyloid Hypothesis.” Stat News. July 30, 2018. Hogan, Alex. “The Disappointing History of Alzheimer’s Research.” Stat News. May 21, 2019. Itzhaki, Ruth. “Alzheimer’s Disease: Mounting Evidence That Herpes Virus Is aCause.” The Conversation. October 19, 2018. Keshavan, Meghana. “On Alzheimer’s, Scientists Head Back to the Drawing Board—and Once-Shunned Ideas Get an Audience.” Stat News. July 22, 2019. Li, Yun. “Biogen Posts It’sthe Worst Day in 14 Years after Ending Trial for Blockbuster Alzheimer’s Drug.” CNBC. March 21, 2019. “Lilly Alzheimer’s Drug Does Not Slow Memory Loss: Study.” CNBC. November 23, 2016. “The MacNeil/Lehrer Report; Living with Alzheimer’s.” 1983-04-12, National Records and Archives Administration, American Archive of Public Broadcasting (WGBH and the Library of Congress), Boston and Washington, DC, accessed October 16, 2019. “The MacNeil/Lehrer NewsHour,” 1991-08-16, NewsHour Productions, American Archive of Public Broadcasting (WGBH and the Library of Congress), Boston, MA and Washington, DC, accessed October 22, 2019. Makin, Simon. “The Amyloid Hypothesis on Trial.”Nature. July 25, 2018. Prusiner, Stanley.Madness and Memory: The Discovery of Prions—A New Biological Principle of Disease.New Haven: Yale University Press, 2014. Robakis, Nikolaos, et al. “Alzheimer’s Disease: A Re-examination of the Amyloid Hypothesis.” ALZforum.org. March 26, 1998. Shenk, David. “The Forgetting—Alzheimer’s: Portrait of an Epidemic.” New York: Anchor, 2013. “Virginia Lee and John Trojanowski on the Protein Road Map to Alzheimer’s.” Science Watch. December 2011.

42 MIN2019 OCT. 23
Comments
The Alzheimer’s Copernicus Problem, Part 2

Preview: The Alzheimer's Copernicus Problem

Listen to The Alzheimer's Copernicus Problem on October 22nd.

3 MIN2019 OCT. 9
Comments
Preview: The Alzheimer's Copernicus Problem

Science on TV

For almost as long as there have been television networks, science shows have been part of the TV landscape. But science programming didn’t begin by accident. At first it was a way for TV stations to build trust with their audiences; then it was used as a ploy to get families to buy more television sets. But as the world changed, so did science on TV. And it turns out that successful science shows have always had one thing in common: they don’t treat their audiences like dummies.

70 MIN2019 SEP. 18
Comments
Science on TV

Latest Episodes

Preview: We're moving to seasons!

Stay tuned for our upcoming season, dropping in summer 2020!

1 MINFEB. 12
Comments
Preview: We're moving to seasons!

How Philadelphia's Water Pollution Problems Shaped the City

Philadelphia just had the wettest decade on record, and all that precipitation has wreaked havoc on the city’s waterways. Like most old cities, Philadelphia has a combined sewer system—that is, one pipe is used to carry both sewage and stormwater. When it rains a lot, the system gets overwhelmed, forcing the water department to send raw sewage into rivers and creeks. City officials and engineersknew this was going to be a problem when they built the sewer system in the 1800s. The reason why they used a combined system anywaycan be best explained by two forces: knowledge ceilings and path dependency.In this episode we’re going to explore how the city got to this pointand how, in an interesting twist, it led to Philadelphia having one of the most innovative water systems in the country. Philadelphia is home of theDistillationspodcast. For this episode we are going to break down three centuries of water-pollution history in our backyard. It is a special collaboration with thePhiladelphia Inquireras part of their seriesFrom the Source: Stories of the Delaware River. Credits Host:Elisabeth Berry Drago Reporter:Rigoberto Hernandez,Sebastian Echeverri Senior Producer:Mariel Carr Producer:Rigoberto Hernandez Audio Engineer:James Morrison Additional production: Dan Drago Special thanks to the Science History Institutes, oral history department, and the museum team for doing someof the research that went into this episode. This includesRebecca Ortenberg,Christy Schneider,Samantha Blatt,Zackary Biro, and Grey Pierce. Resource List Grabar, Henry. “Tunnel Vision.”Slate, January 2, 2019. Handy, Jam. “Waters of the Commonwealth.” Pennsylvania Sanitary Water Board, 1951. Henninger, Danya. “The Incredible Fairmount Water Works: Explosions, Mark Twain and the Long-Lost Philadelphia Aquarium.”Billy Penn, October 10, 2015. Kummer, Frank. “The Secret Scourge of Climate Change? More Raw Sewage in Philadelphia’s Waterways.”Philadelphia Inquirer, September 13, 2019. Levine, Adam. “Fairmount Water Works.” Philadelphia Water Department Water and Drainage History Course, 2015. Nemiroff, Sydney P., dir. “Road Ahead: Milestone 3.” Philadelphia Department of Records, ca. 1960. Schulman, Alexis. “Sustainable Cities and Institutional Change: The Transformation of Urban Stormwater Management.” PhD diss., Massachusetts Institute of Technology, 2018. Stutz, Bruce. “Philadelphia Is Tackling Its Stormwater Problem.”Yale Environment360 (March 29, 2018).

47 MINENE. 8
Comments
How Philadelphia's Water Pollution Problems Shaped the City

Jane Hodgson

She broke abortion law to try to change it.

12 MIN2019 DIC. 18
Comments
Jane Hodgson

Roe v. Wade v. Rubella

The virus that made America talk about abortion.

51 MIN2019 DIC. 18
Comments
Roe v. Wade v. Rubella

Preview: Roe v. Wade v. Rubella

The virus that made America talk about abortion.

2 MIN2019 DIC. 4
Comments
Preview: Roe v. Wade v. Rubella

Promo: LIVE Halloween show!

Come see Distillations LIVE for our Halloween Spooktacular! The show is Wednesday, October 30th at 7pm at the Science History Institute in Old City Philadelphia.

59 s2019 OCT. 24
Comments
Promo: LIVE Halloween show!

The Alzheimer's Copernicus Problem, Part 1

Almost six million people in the United States have been diagnosed with Alzheimer’s disease. And with baby boomers getting older, those numbers are only expected to rise. This disease, despite being studied by scientists for more than 100 years, has no cure. In our two-part series we first dive into the personal lives of the people at the heart of this disease: the patients and their caregivers. Then we uncover why effective treatments for Alzheimer’s lag so far behind those for cancer, heart disease, and HIV. It turns out that for all the decades researchers have been at war with the disease, they’ve also been at war with each other. Credits Hosts:Alexis Pedrick Reporter:Rigoberto Hernandez Producer:Rigoberto Hernandez Senior Producer:Mariel CarrAudio Engineer:James Morrison Music courtesy of theAudio Network. These songs were used courtesy ofBlue Dot Sessions: "Kalsted,""Stretch of Lonely," "Thin Passage," "Waltz and Fury," "Dash and Slope," "Gilroy Solo," 'House of Grendel," "Uncertain Ground," and "Watercool-Quiet." Research Notes “2019 Alzheimer’s Disease Facts and Figures.” Alzheimer’s Association, 2019. Begley, Sharon. “As Alzheimer’s Drug Developers Give Up on Today’s Patients, Where Is the Outrage?” Stat News. August 15, 2018. Begley, Sharon. “The Maddening Saga of How an Alzheimer’s ‘Cabal’ Thwarted Progress toward a Cure for Decades.” Stat News. June 25, 2019. “Biogen Alzheimer’s Drug Shows Positive Results.” CNBC. July 25, 2018. “The Clinical Trial Journey.” Mayo Clinic. Youtube video. June 5, 2019. Garde, Damian. “Alzheimer’s Study Sparks a New Round of Debate over the Amyloid Hypothesis.” Stat News. July 30, 2018. Hogan, Alex. “The Disappointing History of Alzheimer’s Research.” Stat News. May 21, 2019. Itzhaki, Ruth. “Alzheimer’s Disease: Mounting Evidence That Herpes Virus Is aCause.” The Conversation. October 19, 2018. Keshavan, Meghana. “On Alzheimer’s, Scientists Head Back to the Drawing Board—and Once-Shunned Ideas Get an Audience.” Stat News. July 22, 2019. Li, Yun. “Biogen Posts It’sthe Worst Day in 14 Years after Ending Trial for Blockbuster Alzheimer’s Drug.” CNBC. March 21, 2019. “Lilly Alzheimer’s Drug Does Not Slow Memory Loss: Study.” CNBC. November 23, 2016. “The MacNeil/Lehrer Report; Living with Alzheimer’s.” 1983-04-12, National Records and Archives Administration, American Archive of Public Broadcasting (WGBH and the Library of Congress), Boston and Washington, DC, accessed October 16, 2019. “The MacNeil/Lehrer NewsHour,” 1991-08-16, NewsHour Productions, American Archive of Public Broadcasting (WGBH and the Library of Congress), Boston, MA and Washington, DC, accessed October 22, 2019. Makin, Simon. “The Amyloid Hypothesis on Trial.”Nature. July 25, 2018. Prusiner, Stanley.Madness and Memory: The Discovery of Prions—A New Biological Principle of Disease.New Haven: Yale University Press, 2014. Robakis, Nikolaos, et al. “Alzheimer’s Disease: A Re-examination of the Amyloid Hypothesis.” ALZforum.org. March 26, 1998. Shenk, David. “The Forgetting—Alzheimer’s: Portrait of an Epidemic.” New York: Anchor, 2013. “Virginia Lee and John Trojanowski on the Protein Road Map to Alzheimer’s.” Science Watch. December 2011.

46 MIN2019 OCT. 23
Comments
The Alzheimer's Copernicus Problem, Part 1

The Alzheimer’s Copernicus Problem, Part 2

Almost six million people in the United States have been diagnosed with Alzheimer’s disease. And with baby boomers getting older, those numbers are only expected to rise. This disease, despite being studied by scientists for more than 100 years, has no cure. In our two-part series we first dive into the personal lives of the people at the heart of this disease: the patients and their caregivers. Then we uncover why effective treatments for Alzheimer’s lag so far behind those for cancer, heart disease, and HIV. It turns out that for all the decades researchers have been at war with the disease, they’ve also been at war with each other. Credits Hosts:Alexis Pedrick Reporter:Rigoberto Hernandez Producer:Rigoberto Hernandez Senior Producer:Mariel CarrAudio Engineer:James Morrison Music courtesy of theAudio Network. These songs were used courtesy ofBlue Dot Sessions: "Kalsted,""Stretch of Lonely," "Thin Passage," "Waltz and Fury," "Dash and Slope," "Gilroy Solo," 'House of Grendel," "Uncertain Ground," and "Watercool-Quiet." Research Notes “2019 Alzheimer’s Disease Facts and Figures.” Alzheimer’s Association, 2019. Begley, Sharon. “As Alzheimer’s Drug Developers Give Up on Today’s Patients, Where Is the Outrage?” Stat News. August 15, 2018. Begley, Sharon. “The Maddening Saga of How an Alzheimer’s ‘Cabal’ Thwarted Progress toward a Cure for Decades.” Stat News. June 25, 2019. “Biogen Alzheimer’s Drug Shows Positive Results.” CNBC. July 25, 2018. “The Clinical Trial Journey.” Mayo Clinic. Youtube video. June 5, 2019. Garde, Damian. “Alzheimer’s Study Sparks a New Round of Debate over the Amyloid Hypothesis.” Stat News. July 30, 2018. Hogan, Alex. “The Disappointing History of Alzheimer’s Research.” Stat News. May 21, 2019. Itzhaki, Ruth. “Alzheimer’s Disease: Mounting Evidence That Herpes Virus Is aCause.” The Conversation. October 19, 2018. Keshavan, Meghana. “On Alzheimer’s, Scientists Head Back to the Drawing Board—and Once-Shunned Ideas Get an Audience.” Stat News. July 22, 2019. Li, Yun. “Biogen Posts It’sthe Worst Day in 14 Years after Ending Trial for Blockbuster Alzheimer’s Drug.” CNBC. March 21, 2019. “Lilly Alzheimer’s Drug Does Not Slow Memory Loss: Study.” CNBC. November 23, 2016. “The MacNeil/Lehrer Report; Living with Alzheimer’s.” 1983-04-12, National Records and Archives Administration, American Archive of Public Broadcasting (WGBH and the Library of Congress), Boston and Washington, DC, accessed October 16, 2019. “The MacNeil/Lehrer NewsHour,” 1991-08-16, NewsHour Productions, American Archive of Public Broadcasting (WGBH and the Library of Congress), Boston, MA and Washington, DC, accessed October 22, 2019. Makin, Simon. “The Amyloid Hypothesis on Trial.”Nature. July 25, 2018. Prusiner, Stanley.Madness and Memory: The Discovery of Prions—A New Biological Principle of Disease.New Haven: Yale University Press, 2014. Robakis, Nikolaos, et al. “Alzheimer’s Disease: A Re-examination of the Amyloid Hypothesis.” ALZforum.org. March 26, 1998. Shenk, David. “The Forgetting—Alzheimer’s: Portrait of an Epidemic.” New York: Anchor, 2013. “Virginia Lee and John Trojanowski on the Protein Road Map to Alzheimer’s.” Science Watch. December 2011.

42 MIN2019 OCT. 23
Comments
The Alzheimer’s Copernicus Problem, Part 2

Preview: The Alzheimer's Copernicus Problem

Listen to The Alzheimer's Copernicus Problem on October 22nd.

3 MIN2019 OCT. 9
Comments
Preview: The Alzheimer's Copernicus Problem

Science on TV

For almost as long as there have been television networks, science shows have been part of the TV landscape. But science programming didn’t begin by accident. At first it was a way for TV stations to build trust with their audiences; then it was used as a ploy to get families to buy more television sets. But as the world changed, so did science on TV. And it turns out that successful science shows have always had one thing in common: they don’t treat their audiences like dummies.

70 MIN2019 SEP. 18
Comments
Science on TV

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